Ingression of acids into concrete structure arrests its long-term durability by the progressive degradation of the highly alkaline cementitious materials. Acid attack results in the decalcification of hydration products leading to higher inherent porosity and both micro-macro cracks, providing a path for the passage of aggressive ions into the interior of concrete. Amplification of agriculture and food industries such as the breeding, dairy or sugar industries produce large quantities of effluents that are the major sources of organic acids. These effluents have complex acidic compositions leading to serious degradation of structures made for their production, collection, storage and treatment. New binder systems that are capable of proposing extensive long term durability in aggressive acidic environment and also being a sustainable option need to be evolved. From earlier studies, application of various binder systems containing materials such as fly ash, ground granulated blast furnace slag, silica fume, bagasse ash etc. has an influence on the hydration products, micro-structural and macro-structural changes in cement-based materials when subjected to aggressive acidic media, thus enhancing the performance and durability of concrete structures. This paper outlines the basic mechanism of organic acid attack and highlights the influence of various binder systems on the alteration of degradation kinetics when exposed to various organic acids.