%0 Journal Article %T Designing P-Chirogenic 1,2-Diphosphinobenzenes at Both P-Centers Using P(III)-Phosphinites %+ Institut de Chimie Moléculaire de l'Université de Bourgogne [Dijon] (ICMUB) %A Bayardon, Jérôme %A Rousselin, Yoann %A Jugé, Sylvain %Z CNRS (Centre National de la Recherche Scientifique) %Z Ministère de l’Éducation Nationale et de la Recherche %Z Conseil Régional de Bourgogne 3MIM Pad II-CDEA/smt8 %Z Agence Nationale pour la Recherche 07BLAN292-01 %< avec comité de lecture %@ 1523-7060 %J Organic Letters %I American Chemical Society %V 18 %N 12 %P 2930 - 2933 %8 2016-05-31 %D 2016 %R 10.1021/acs.orglett.6b01275 %K catalyzed asymmetric hydrogenation %K highly enantioselective hydrogenation %K functionalized alkenes %K phospholane ligands %K phosphine-ligands %K carbon-monoxide %K hydroformylation %K ketones %K organocatalysis %K derivatives %Z Chemical Sciences %Z Chemical Sciences/Organic chemistryJournal articles %X A new enantiodivergent synthesis of P-chirogenic 1,2-diphosphinobenzenes (DP*B) bearing the chirality on one or both phosphorus centers is reported using aryne chemistry. The principle is based on successive reactions of 1,2-dibromobenzene with sec-phosphide boranes, then DABCO to remove the borane, and finally with chlorophosphines or P(III)-chirogenic phosphinites. The efficiency of this synthesis was demonstrated by the stereoselective preparation of (S,S)-1,2-bis(o-anisylphenylphosphino)benzene. A comparison of DIPAMP and homochiral DP*B ligands in asymmetric Rh- or Pd-catalyzed reactions was reported. %G English %L hal-01403243 %U https://u-bourgogne.hal.science/hal-01403243 %~ UNIV-BOURGOGNE %~ CNRS %~ ICMUB %~ INC-CNRS %~ TEST2-HALCNRS