Outcomes of Transcatheter Arterial Embolization with a Modified N-Butyl Cyanoacrylate Glue for Spontaneous Iliopsoas and Rectus Sheath Hematomas in Anticoagulated Patients - Université de Bourgogne Accéder directement au contenu
Article Dans Une Revue JVIR: Journal of Vascular and Interventional Radiology Année : 2018

Outcomes of Transcatheter Arterial Embolization with a Modified N-Butyl Cyanoacrylate Glue for Spontaneous Iliopsoas and Rectus Sheath Hematomas in Anticoagulated Patients

Résumé

Purpose To assess the efficacy and safety of n-butyl cyanoacrylate methacryloxy sulfolane (NBCA-MS) transcatheter arterial embolization for anticoagulation-related soft-tissue bleeding and to evaluate predictive factors of clinical success and 30-day mortality. Materials and Methods A retrospective review of 50 anticoagulated patients (25 male; mean age, 71.7 y ± 14.2; range, 19–87 y) who underwent emergent Glubran 2 NBCA-MS embolization for iliopsoas hematomas (IPHs; n = 38), rectus sheath hematomas (n = 11), or both (n = 1) between 2011 and 2016 was performed. Inclusion criteria were active bleeding on computed tomography (CT) and anticoagulation. The mean number of red blood cell (RBC) units transfused was 4.8 ± 3.2 (range, 0–14), median hemoglobin level before embolization was 9.7 g/dL (range, 6.2–18 g/dL), and median “mean blood pressure” (MBP) was 62.5 mm Hg (range, 58.3–75 mm Hg). Mean International Normalized Ratio before intervention was 2.5 ± 1.5 (range, 1.0–6.9). Angiograms revealed extravasation in 44 of 50 patients (88%). Mean hematoma volume was 1,119.2 cm3 ± 863.5 (range, 134.0–3,589.0 cm3). Results Technical success was achieved in 100% of patients, and 30-day clinical success was achieved in 66% of patients. Recurrent bleeding and mortality rates within 30 days of embolization were 34% and 44%, respectively. No complications related to the embolization procedure occurred. Lower MBP (P = .003), greater number of RBC units transfused (P = .003), greater volume of hematoma (P = .04), and IPH location (P = .02) were associated with decreased clinical success. Clinical failure (P = .00002), lower MBP (P = .004), greater number of RBC units transfused (P = .002), and IPH location (P = .01) were significantly associated with higher 30-day mortality rates. Conclusions Transcatheter arterial embolization with NBCA-MS is safe and effective in treating refractory soft-tissue bleeding in anticoagulated patients despite the high mortality rates associated with this patient population. Copyright © 2017 SIR. Published by Elsevier Inc. All rights reserved.
Fichier non déposé

Dates et versions

hal-01731267 , version 1 (14-03-2018)

Identifiants

Citer

Rany Jawhari, Olivier Chevallier, Nicolas Falvo, Philippe d'Athis, Sophie Gehin, et al.. Outcomes of Transcatheter Arterial Embolization with a Modified N-Butyl Cyanoacrylate Glue for Spontaneous Iliopsoas and Rectus Sheath Hematomas in Anticoagulated Patients. JVIR: Journal of Vascular and Interventional Radiology, 2018, 29 (2), pp.210 - 217. ⟨10.1016/j.jvir.2017.08.006⟩. ⟨hal-01731267⟩
34 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More