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Article Dans Une Revue Genomics Année : 1994

Cloning of Two Novel ABC Transporters Mapping on Human Chromosome 9

Résumé

The family of ATP binding cassette (ABC) transporters or traffic ATPases is composed of several membrane-associated proteins that transport a great variety of solutes across cellular membranes. Two novel mammalian members of the family, ABC1 and ABC2, have been identified by a PCR-based approach. They belong to a group of traffic ATPases encoded as a single multifunctional protein, such as CFTR, STE 6, and P-glycoproteins. Their peculiar structural features and close relationship to ABC transporters involved in nodulation suggest that ABC1 and ABC2 define a novel subgroup of mammalian traffic ATPases.

Dates et versions

hal-04342121 , version 1 (13-12-2023)

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Marie Françoise Luciani, François Denizot, Stéphane Savary, Marie Geneviève Mattei, Giovanna Chimini. Cloning of Two Novel ABC Transporters Mapping on Human Chromosome 9. Genomics, 1994, 21 (1), pp.150-159. ⟨10.1006/geno.1994.1237⟩. ⟨hal-04342121⟩
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